A novel, antigen-presenting function of melanocytes and its possible relationship to hypopigmentary disorders.

@article{Poole1993ANA,
  title={A novel, antigen-presenting function of melanocytes and its possible relationship to hypopigmentary disorders.},
  author={I Caroline Le Poole and Tuna Mutis and R M van den Wijngaard and Wiete Westerhof and TomH. M Ottenhoff and Rene Penning de Vries and Pranab Kumar Das},
  journal={Journal of immunology},
  year={1993},
  volume={151 12},
  pages={7284-92}
}
It is now well established that cultured human melanocytes are capable of expressing immunologically important cell surface molecules and that they can produce cytokines. Not all cells with the ability to express MHC class II molecules are capable of effective Ag presentation. However, the dendritic nature of melanocytes, their strategic position within the skin, and their phagocytic capacity seem to suggest a role for these cells in processing and presenting Ag. This study demonstrates that… CONTINUE READING

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