A note on the power prior.

  title={A note on the power prior.},
  author={Beat Neuenschwander and Michael Branson and David J. Spiegelhalter},
  journal={Statistics in medicine},
  volume={28 28},
The power prior by Ibrahim and Chen (Statist. Sci. 2000; 15:46-60) is one of several methods to incorporate historical data in the analysis of a clinical trial. The power prior raises the likelihood of the historical data to the power parameter a(0) which quantifies the discounting of the historical data due to heterogeneity between trials. It is shown that the standard method of estimating the power parameter from the historical and current data is inappropriate, and we therefore suggest to… CONTINUE READING