A note on efficient estimation of mutation rates using Luria-Delbrück fluctuation analysis.

Abstract

The maximum likelihood and Luria-Delbrück P0 methods for the estimation of spontaneous mutation rates are compared. The maximum likelihood method is fully efficient, utilizing all available information in a fluctuation experiment, but can be numerically cumbersome. Under certain conditions, there is little loss of efficiency using the P0 method, which is… (More)

Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.