Corpus ID: 56226671

A nonsense mutation in the porcine myostatin gene is a candidate causative variant for a recessive leg weakness syndrome and affects muscle depth

@inproceedings{Matika2018ANM,
  title={A nonsense mutation in the porcine myostatin gene is a candidate causative variant for a recessive leg weakness syndrome and affects muscle depth},
  author={O. Matika and D. Robledo and R. Pong-Wong and J. Woolliams and S. Bishop and V. Riggio and A E. and Hoste and G. Walling and A. Archibald and R. Houston},
  year={2018}
}
Lameness in piglets is a major animal welfare and economic problem in pig production. Following observation of a high incidence of a leg weakness syndrome in a commercial pig lines, a variance components approach was used to assess the genetic basis of the condition. The results suggested a monogenic recessive mode of inheritance, and homozygosity mapping was used to identify a region associated with the leg weakness syndrome on SSC15. Whole genome resequencing of cases and controls identified… Expand

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