A noninvasive genetic/pharmacologic strategy for visualizing cell morphology and clonal relationships in the mouse.

@article{Badea2003ANG,
  title={A noninvasive genetic/pharmacologic strategy for visualizing cell morphology and clonal relationships in the mouse.},
  author={Tudor Constantin Badea and Yanshu Wang and Jeremy Nathans},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2003},
  volume={23 6},
  pages={2314-22}
}
Analysis of cellular morphology is the most general approach to neuronal classification. With the increased use of genetically engineered mice, there is a growing need for methods that can selectively visualize the morphologies of specified subsets of neurons. This capability is needed both to define cell morphologic phenotypes and to mark cells in a noninvasive manner for lineage studies. To this end, we describe a bipartite genetic system based on a Cre-estrogen receptor (ER) fusion protein… CONTINUE READING
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