A nonintrinsic regional basis for increased infrarenal aortic MMP-9 expression and activity.

Abstract

OBJECTIVE This investigation was undertaken to determine whether intrinsic or regional factors at different anatomic sites of the aorta affect expression and activity of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs). METHODS Aortas from Sprague-Dawley rats (n = 22) were divided into arch, descending thoracic, and… (More)

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