A non-peptide oxytocin receptor agonist, WAY-267,464, alleviates novelty-induced hypophagia in mice: insights into changes in c-Fos immunoreactivity.

@article{Olszewski2014ANO,
  title={A non-peptide oxytocin receptor agonist, WAY-267,464, alleviates novelty-induced hypophagia in mice: insights into changes in c-Fos immunoreactivity.},
  author={Pawel Karol Olszewski and Christine Ulrich and Nicholas Ling and Kerry Allen and Allen Stuart Levine},
  journal={Pharmacology, biochemistry, and behavior},
  year={2014},
  volume={124},
  pages={367-72}
}
Anxiety caused by the novelty of food or of the environment where the food is presented leads to suppression of consumption (hyponeophagia) reflected by an increased latency to begin feeding and decreased food intake. Studies suggest that some anxiolytics, mainly benzodiazepines and SSRIs, resolve hyponeophagia. Though the neurohormone oxytocin (OT) affects both anxiety responsiveness and feeding-related homeostasis, the link between OT and hyponeophagia has not been established. The current… CONTINUE READING