A non-cycling mitotic cyclin in the naturally synchronous cell cycle of Physarum polycephalum.

@article{Cho1994ANM,
  title={A non-cycling mitotic cyclin in the naturally synchronous cell cycle of Physarum polycephalum.},
  author={Jennifer Whelden Cho and Helmut W. Sauer},
  journal={European journal of cell biology},
  year={1994},
  volume={65 1},
  pages={94-102}
}
A universal model of the control of the cell cycle in eukaryotic organisms has emerged from the discovery that MPF (maturation or mitosis promoting factor) is a heterodimer consisting of a catalytic subunit (p34cdc2) and a regulatory subunit (mitotic cyclin) encoded by a pair of conserved genes. A prominent feature of the periodic activation of the protein kinase p34cdc2 is the gradual accumulation of cyclin in interphase and its abrupt degradation in mitosis, which is believed to be required… CONTINUE READING