A nomenclature for the mammalian flavin-containing monooxygenase gene family based on amino acid sequence identities.

@article{Lawton1994ANF,
  title={A nomenclature for the mammalian flavin-containing monooxygenase gene family based on amino acid sequence identities.},
  author={Michael P. Lawton and John Richard Cashman and Thierry Cresteil and Colin T. Dolphin and Adnan A. Elfarra and Ronald N Hines and Ernest Hodgson and Toshiaki Kimura and Juris Ozols and Ian R. Phillips},
  journal={Archives of biochemistry and biophysics},
  year={1994},
  volume={308 1},
  pages={254-7}
}
A nomenclature based on comparisons of amino acid sequences is proposed for the members of the mammalian flavin-containing monooxygenase (FMO) gene family. This nomenclature is based on evidence of a single gene family composed of five genes. The percentage identities of the amino acid sequences of the five known forms of mammalian FMO are between 52 and 57% in rabbit and between 50 and 58% across species lines. The identities of all orthologs are greater than 82%. There is no evidence for… CONTINUE READING