A newly identified MAGE-3-derived, HLA-A24-restricted peptide is naturally processed and presented as a CTL epitope on MAGE-3-expressing gastrointestinal cancer cells.

@article{Miyagawa2006ANI,
  title={A newly identified MAGE-3-derived, HLA-A24-restricted peptide is naturally processed and presented as a CTL epitope on MAGE-3-expressing gastrointestinal cancer cells.},
  author={Naoto Miyagawa and Koji Kono and Kousaku Mimura and Hideo Omata and Hidemitsu Sugai and Hideki Fujii},
  journal={Oncology},
  year={2006},
  volume={70 1},
  pages={54-62}
}
PURPOSE In order to broaden the possibility for anti-MAGE-3 immune targeting, it is important to identify HLA-A24-restricted epitopes derived from MAGE-3, since HLA-A24 is one of the most common alleles in Japanese and Asian people. In the present study, we defined a new MAGE-3 derived, HLA-A24-binding peptide presented as a CTL epitope on gastrointestinal… CONTINUE READING