A new view of Starling's hypothesis at the microstructural level.

@article{Hu1999ANV,
  title={A new view of Starling's hypothesis at the microstructural level.},
  author={Xin Hu and Sheldon Weinbaum},
  journal={Microvascular research},
  year={1999},
  volume={58 3},
  pages={281-304}
}
In this paper we quantitatively investigate the hypothesis proposed by Michel (Exp. Physiol. 82, 1-30, 1997) and Weinbaum (Ann. Biomed. Eng. 26, 1-17, 1998) that the Starling forces are determined by the local difference in the hydrostatic and colloid osmotic pressure across the endothelial surface glycocalyx, which we propose is the primary molecular sieve for plasma proteins, rather than the global difference in the hydrostatic and oncotic pressure across the capillary wall between the plasma… CONTINUE READING
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