A new usage of functionalized oligodeoxynucleotide probe for site-specific modification of a guanine base within RNA


Site-specific modification of RNA is of great significance to investigate RNA structure, function and dynamics. Recently, we reported a new method for sequence- and cytosine-selective chemical modification of RNA based on the functional group transfer reaction of the 1-phenyl-2-methylydene-1,3-diketone unit of the 6-thioguanosine base incorporated in the… (More)
DOI: 10.1093/nar/gkp930


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