A new turn-on fluorescence probe for Zn(2+) in aqueous solution and imaging application in living cells.

Abstract

We designed and synthesized a new pyrazoline-based turn-on fluorescence probe for Zn(2+) by the reaction of chalcone and thiosemicarbazide. The structure of the probe was characterized by IR, NMR and HRMS spectroscopy. The probe (L) exhibits high selectivity and sensitivity for detecting Zn(2+) in buffered EtOH/HEPES solution (EtOH/HEPES=1/1, pH 7.2) with… (More)
DOI: 10.1016/j.aca.2014.04.001

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