A new trimethoprim resistance gene, dhfrX, in the In7 integron of plasmid pDGO100.

@article{Parsons1991ANT,
  title={A new trimethoprim resistance gene, dhfrX, in the In7 integron of plasmid pDGO100.},
  author={Y M Parsons and Ruth M Hall and H. W. Stokes},
  journal={Antimicrobial agents and chemotherapy},
  year={1991},
  volume={35 11},
  pages={2436-9}
}
A new trimethoprim resistance determinant, designated dhfrX, was identified in the In7 integron of pDGO100. The sequence of the dhfrX dihydrofolate reductase is up to 28% identical to the sequences of several known dihydrofolate reductase proteins. The dhfrX gene is adjacent to the second 3'-conserved segment of the In7 integron, but the first 77 bases of this segment are not present.