A new strategy to screen molecular imaging probe uptake in cell culture without radiolabeling using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.

@article{Cheng2005ANS,
  title={A new strategy to screen molecular imaging probe uptake in cell culture without radiolabeling using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.},
  author={Zhen Cheng and Richard C Winant and Sanjiv Sam Gambhir},
  journal={Journal of nuclear medicine : official publication, Society of Nuclear Medicine},
  year={2005},
  volume={46 5},
  pages={878-86}
}
UNLABELLED Numerous new molecular targets for diseases are rapidly being identified and validated in the postgenomic era, urging scientists to explore novel techniques for accelerating molecular probe development. In this study, matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS) was investigated as a potential tool for high-throughput screening and characterization of molecular imaging probes. Specifically, MALDI-TOF-MS was used to screen a small library… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-9 of 9 extracted citations

Pituitary adenoma biomarkers identified using proteomic fingerprint technology.

Asian Pacific journal of cancer prevention : APJCP • 2012
View 2 Excerpts
Highly Influenced

Evaluation of a mitochondrial voltage sensor, (18F-fluoropentyl)triphenylphosphonium cation, in a rat myocardial infarction model.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine • 2012
View 1 Excerpt

Similar Papers

Loading similar papers…