A new strategy for the early diagnosis of rheumatoid arthritis: a combined approach.

@article{Tedesco2009ANS,
  title={A new strategy for the early diagnosis of rheumatoid arthritis: a combined approach.},
  author={Angela Tedesco and Daniel D'agostino and I. Soriente and Paula Amato and Roberto Piccoli and Paola Sabatini},
  journal={Autoimmunity reviews},
  year={2009},
  volume={8 3},
  pages={
          233-7
        }
}
Rheumatoid arthritis [RA] is one of the most common and severe autoimmune rheumatic diseases, diagnosed primarily according to clinical manifestations and radiological reports. For many years, laboratory diagnosis of rheumatoid arthritis has relied on the detection of rheumatoid factor [RF], as established by the ACR criteria. A recent test to detect antibodies towards citrullinated peptides, called the anti-CCP assay, showed a similar sensitivity but a more elevated specificity than the RF… CONTINUE READING

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