A new step toward the artificial ovary: survival and proliferation of isolated murine follicles after autologous transplantation in a fibrin scaffold.

@article{Luyckx2014ANS,
  title={A new step toward the artificial ovary: survival and proliferation of isolated murine follicles after autologous transplantation in a fibrin scaffold.},
  author={Val{\'e}rie Luyckx and Marie-Madeleine Dolmans and Julie Vanacker and Camille Legat and Cristina Fortu{\~n}o Moya and Jacques Donnez and Christiani A Amorim},
  journal={Fertility and sterility},
  year={2014},
  volume={101 4},
  pages={1149-56}
}
OBJECTIVE To create an artificial ovary to provide an alternative way of restoring fertility in patients who cannot benefit from transplantation of cryopreserved ovarian tissue due to the threat of reintroducing malignant cells. DESIGN In vivo experimental study. SETTING Gynecology research unit in a university hospital. ANIMAL(S) Six-week-old female NMRI mice. INTERVENTION(S) Autografting of isolated preantral follicles and ovarian cells (OCs) encapsulated in two fibrin matrices… CONTINUE READING
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