A new specific, sensitive and non-carcinogenic reagent for the demonstration of horseradish peroxidase

@article{Hanker1977ANS,
  title={A new specific, sensitive and non-carcinogenic reagent for the demonstration of horseradish peroxidase},
  author={Jacob S. Hanker and Peggy E. Yates and Carol B. Metz and Aldo Rustioni},
  journal={The Histochemical Journal},
  year={1977},
  volume={9},
  pages={789-792}
}
3,3'-Diaminobenzidine (DAB), introduced by Graham & Karnovsky (J. Histochem. Cytochem. 1966, 14, 291 & J. exp. Med. 1966, 124, 1123) is one of the most widely employed reagents in histochemistry. It has been very useful in demonstrating the sites to which the exogenous ultrastructural tracer horseradish peroxidase (HRP) is transported in vertebrate tissues. Over the past five years, DAB staining of transported HRP in neurons has developed into a powerful neuroanatomical tool for labelling the… CONTINUE READING
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