A new small myotoxin from the venom of the prairie rattlesnake (Crotalus viridis viridis)

@article{Griffin1990ANS,
  title={A new small myotoxin from the venom of the prairie rattlesnake (Crotalus viridis viridis)},
  author={Patrick R. Griffin and Steven D Aird},
  journal={FEBS Letters},
  year={1990},
  volume={274}
}
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21 Citations
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21 Citations

Characterization of the two myotoxin a isomers from the prairie rattlesnake (Crotalus viridis viridis) by capillary zone electrophoresis and fluorescence quenching studies.
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    Toxicon : official journal of the International Society on Toxinology
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A simple and rapid method for isolating small myotoxins from rattlesnake venoms.
  • Q. Li, T. Colberg, C. Ownby
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Evidence for isomerization in myotoxin a from the prairie rattlesnake (Crotalus viridis viridis).
Regional differences in content of small basic peptide toxins in the venoms of Crotalus adamanteus and Crotalus horridus.
The nucleotide sequence of the translated and untranslated regions of a cDNA for myotoxin a from the venom of prairie rattlesnake (Crotalus viridis viridis).
TLDR
It is likely that myot toxin a is secreted as the cDNA encodes a signal peptide immediately 5' to the myotoxin a peptide code.
Structural and Biological Characterization of Two Crotamine Isoforms IV-2 and IV-3 Isolated from the Crotalus durissus cumanensis Venom
TLDR
These new crotamine isoforms induced potent blockade of neuromuscular transmission in young chicken biventer cervicis preparation and potent myotoxic effect in mice, modulated by the presence of positively charged amino acid residues.
Individual expression patterns of myotoxin isoforms in the venom of the snake Bothrops asper.
  • B. Lomonte, E. Carmona
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    Comparative biochemistry and physiology. B, Comparative biochemistry
  • 1992
Structure, Function and Biophysical Aspects of the Myotoxins from Snake Venoms
TLDR
The purpose of this review is to describe the structure and function of these myotoxins and to evaluate features they might share which could shed light on the function and structure of snake venom toxins.
Neutralization of crotamine by polyclonal antibodies generated against two whole rattlesnake venoms and a novel recombinant fusion protein.
Nucleotide sequence of crotamine isoform precursors from a single South American rattlesnake (Crotalus durissus terrificus).
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References

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Characterization of myotoxin a from the venom of prairie rattlesnake (Crotalus viridis viridis).
TLDR
The circular dichroic spectrum indicates that the chemically modified, inactive myotoxin exhibits typical random-coil conformation.
Characterization of Two Myotoxic Proteins from Venom of Crotalus viridis concolor
TLDR
The fractionation of the previously unstudied venom for Crotalus viridis concolor provided a protein fraction (FD-1) that generated myotoxic responses from envenomated mice that cause extensive damage to the sarcoplasmic reticulum as evidenced by electron microscopic studies of en venomated muscle.
Some chemical properties of the venom of the rattlesnake, Crotalus viridis helleri.
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TLDR
Methodology for determining amino acid sequences of proteins by tandem mass spectrometry, and Interpretation of collision-activated dissociation mass spectra is described, results are presented from a study of soluble peptides produced by treatment of apolipoprotein B with cyanogen bromide and trypsin.
Feminine Motifs in Bodhidharma Symbology in Japan
ZEN AND POPULAR DEPICTIONS OF DARUMA In the tradition and lore of Buddhism in East Asia a very conspicuous figure is Bodhidharma, an immigrant Indian monk credited with having begun the development…
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W5 tASHINGTON IRVING began Astoria with the avowed V11/ Vintention of providing his readers with a picture of American enterprise as it was manifested in the fur trade. His subject was Colonel John…
Amino acid sequence and disulfide bond assignment of myotoxin a isolated from the venom of Prairie rattlesnake (Crotalus viridis viridis).
TLDR
Myotoxin a did not show any close relationship to other toxins except crotamine from the South American rattlesnake Crotalus durissus terrificus and was compared with the sequences of other snake venom toxins using the computer program RELATE to determine whether myot toxin a is similar to any other types of toxins.
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