A new sandwich immunoassay for detection of the α-secretase cleaved, soluble amyloid-β protein precursor in cerebrospinal fluid and serum.

Abstract

Alzheimer's disease (AD) is the most common neurodegenerative disorder. Frequently used diagnostic biomarkers are amyloid-β42 (Aβ42), tau, and phospho-tau, which are measured in cerebrospinal fluid (CSF), and allow a reasonable, but not full, separation of AD patients and controls. Besides Aβ42, additional proteolytic cleavage products of the amyloid… (More)
DOI: 10.3233/JAD-130509

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Cite this paper

@article{Taverna2013ANS, title={A new sandwich immunoassay for detection of the α-secretase cleaved, soluble amyloid-β protein precursor in cerebrospinal fluid and serum.}, author={M. J. Taverna and Tobias Straub and Harald Hampel and Dan Rujescu and Stefan F. Lichtenthaler}, journal={Journal of Alzheimer's disease : JAD}, year={2013}, volume={37 4}, pages={667-78} }