A new protein superfamily includes two novel 3-methyladenine DNA glycosylases from Bacillus cereus, AlkC and AlkD

@article{Alseth2006ANP,
  title={A new protein superfamily includes two novel 3-methyladenine DNA glycosylases from Bacillus cereus, AlkC and AlkD},
  author={Ingrun Alseth and Torbj\orn Rognes and Toril Lindb{\"a}ck and Inger Camilla Solberg and Kristin Robertsen and Knut Ivan Kristiansen and Davide Mainieri and Lucy Lillehagen and Anne-Brit Kolst\o and Magnar Bj\or{\aa}s},
  journal={Molecular Microbiology},
  year={2006},
  volume={59},
  pages={1602 - 1609}
}
Soil bacteria are heavily exposed to environmental methylating agents such as methylchloride and may have special requirements for repair of alkylation damage on DNA. We have used functional complementation of an Escherichia coli tag alkA mutant to screen for 3-methyladenine DNA glycosylase genes in genomic libraries of the soil bacterium Bacillus cereus. Three genes were recovered: alkC, alkD and alkE. The amino acid sequence of AlkE is homologous to the E. coli AlkA sequence. AlkC and AlkD… CONTINUE READING

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Repair of alkylation

  • E. 2569–2573. Seeberg, K. G. Berdal
  • 1997
Highly Influential
5 Excerpts

Repair of alkylation damage to DNA

  • E. Seeberg, K. G. Berdal
  • Base Excision Repair of DNA Damage .
  • 1997
Highly Influential
4 Excerpts

The Authors Journal compilation

  • I. Alseth
  • Blackwell Publishing Ltd, Molecular Microbiology,
  • 2006

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