A new prostate carcinoma binding peptide (DUP-1) for tumor imaging and therapy.

@article{Zitzmann2005ANP,
  title={A new prostate carcinoma binding peptide (DUP-1) for tumor imaging and therapy.},
  author={Sabine Zitzmann and Walter Mier and Arno Schad and Ralf Kinscherf and Vasileios Askoxylakis and Susanne Kr{\"a}mer and Annette Altmann and Michael Eisenhut and Uwe Haberkorn},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  year={2005},
  volume={11 1},
  pages={139-46}
}
PURPOSE Prostate carcinomas belong to the most widespread tumors, and their number is increasing. Imaging modalities used for diagnosis, such as ultrasound, computed tomography, and positron emission tomography, often produce poor results. Radiolabeled peptides with high sensitivity and specificity for prostate cancer would be a desirable tool for tumor diagnosis and treatment. EXPERIMENTAL DESIGN We used phage display and the prostate-specific membrane antigen-negative cell line DU-145 to… CONTINUE READING