A new platelet cryoprecipitate glue promoting bone formation after ectopic mesenchymal stromal cell-loaded biomaterial implantation in nude mice

@inproceedings{Trouillas2012ANP,
  title={A new platelet cryoprecipitate glue promoting bone formation after ectopic mesenchymal stromal cell-loaded biomaterial implantation in nude mice},
  author={Marina Trouillas and Marie Prat and Christelle Doucet and Isabelle Ernou and Corinne Laplace-Builhe and Patrick Saint Blancard and Xavier Holy and Jean-jacques Lataillade},
  booktitle={Stem Cell Research & Therapy},
  year={2012}
}
IntroductionThis study investigated the promising effect of a new Platelet Glue obtained from Cryoprecipitation of Apheresis Platelet products (PGCAP) used in combination with Mesenchymal Stromal Cells (MSC) loaded on ceramic biomaterials to provide novel strategies enhancing bone repair.MethodsPGCAP growth factor content was analyzed by ELISA and compared to other platelet and plasma-derived products. MSC loaded on biomaterials (65% hydroxyapatite/35% beta-TCP or 100% beta-TCP) were embedded… CONTINUE READING

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