A new pheromone trail-based genetic algorithm for comparative genome assembly

@inproceedings{Zhao2008ANP,
  title={A new pheromone trail-based genetic algorithm for comparative genome assembly},
  author={Fangqing Zhao and Fanggeng Zhao and Tao Li and Donald A Bryant},
  booktitle={Nucleic acids research},
  year={2008}
}
Gap closing is considered one of the most challenging and time-consuming tasks in bacterial genome sequencing projects, especially with the emergence of new sequencing technologies, such as pyrosequencing, which may result in large amounts of data without the benefit of large insert libraries for contig scaffolding. We propose a novel algorithm to align contigs with more than one reference genome at a time. This approach can successfully overcome the limitations of low degrees of conserved gene… CONTINUE READING
Highly Cited
This paper has 27 citations. REVIEW CITATIONS

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 14 citations