A new paradigm for the prediction of antidepressant treatment response

  title={A new paradigm for the prediction of antidepressant treatment response},
  author={Andrew F. Leuchter and Ian A. Cook and A M Hunter and Alexander S. Korb},
  booktitle={Dialogues in clinical neuroscience},
Current treatment of Major Depressive Disorder utilizes a trial-and-error sequential treatment strategy that results in delays in achieving response and remission for a majority of patients. Protracted ineffective treatment prolongs patient suffering and increases health care costs. In addition, long and unsuccessful antidepressant trials may diminish patient expectations, reinforce negative cognitions, and condition patients not to respond during subsequent antidepressant trials, thus… CONTINUE READING
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Changes in brain function (QEEG cordance) during placebo lead-in and SCL-90-R symptom dimension changes in MDD during randomized treatment with antidepressant or placebo

  • AM Hunter, S Ravikumar, IA Cook, AF. Leuchter
  • Acta Psychiatrica Scandinavica
  • 2009

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