A new paradigm for the diagnosis and management of unknown primary tumors of the head and neck: A role for transoral robotic surgery

@article{Mehta2013ANP,
  title={A new paradigm for the diagnosis and management of unknown primary tumors of the head and neck: A role for transoral robotic surgery},
  author={Vikas Mehta and Paul Johnson and Andrew B. Tassler and Seungwon Kim and Robert L Ferris and Melonie Nance and Jonas T. Johnson and U. Duvvuri},
  journal={The Laryngoscope},
  year={2013},
  volume={123}
}
In 2% to 3% of patients with cancer metastatic to cervical lymph nodes, a primary tumor will not be found despite exhaustive diagnostic efforts. The treatment for these patients includes cervical lymphadenectomy followed by radiation to areas with increased risk of harboring a mucosal primary. Wide‐field radiation therapy increases the incidence of xerostomia and dysphagia. Localizing a primary tumor has thus both therapeutic and quality‐of‐life implications, allowing possible complete surgical… 

Transoral robotic surgery for carcinoma of unknown primary in the head and neck

The authors' treatment paradigm is presented and the literature supporting the use of TORS in the management of CUP is reviewed, highlighting its importance in optimizing identification and resection of the primary tumor.

Role of Transoral Robotic Surgery in the Work-up of the Unknown Primary.

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Transoral robotic surgery (TORS) has proven to be an effective technique to safely treat oropharyngeal and select supraglottic tumors surgically and the literature supports its safety and efficacy based on numerous studies.

Transoral Robotic Surgery and the Unknown Primary

The indication, surgical technique, evidence base, and controversies of performing TORS in the context of the unknown primary are presented.

When is surgical therapy for head and neck malignant epithelial tumors not indicated?

The reasons for recommending non-surgical therapies for certain epithelial cancers of the head and neck are examined, weighed against the best quality of life and functional outcomes after treatment.

Transoral Robotic Surgery–Assisted Endoscopy With Primary Site Detection and Treatment in Occult Mucosal Primaries

The efficacy of a TORS-assisted approach to identify and surgically treat the primary tumor in patients presenting with CUP is demonstrated and results in deintensification of treatment by eliminating the need for chemotherapy in the majority of patients, as well as avoiding radiation therapy in select patients.

Transoral robotic surgery base of tongue mucosectomy for head and neck cancer of unknown primary

Head and neck cancer of unknown primary (HNCUP) is a source of diagnostic uncertainty. Patients presenting with cytologically positive neck lumps without a clinically identifiable primary, require

Finding/identifying primaries with neck disease (FIND) clinical trial protocol: a study integrating transoral robotic surgery, histopathological localisation and tailored deintensification of radiotherapy for unknown primary and small oropharyngeal head and neck squamous cell carcinoma

This study aims to assess the oncological and functional outcomes of a combined treatment approach with TORS and tailored radiotherapy according to the location and laterality of the primary tumour.

The Role of Transoral Robotic Surgery in the Management of Oropharyngeal Squamous Cell Carcinoma: a Current Review

Transoral robotic surgery (TORS) is a minimally invasive surgical approach that offers surgical access to the oropharynx without the morbidity of open procedures while achieving excellent oncologic and functional outcomes.
...

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