A new paradigm for operant conditioning of Drosophila melanogaster

@article{Wustmann2004ANP,
  title={A new paradigm for operant conditioning of Drosophila melanogaster},
  author={Gerhard Wustmann and Karlheinz Rein and Reinhard Wolf and Martin Heisenberg},
  journal={Journal of Comparative Physiology A},
  year={2004},
  volume={179},
  pages={429-436}
}
A freely walking single fly (Drosophila melanogaster) can be conditioned to avoid one side of a small test chamber if the chamber is heated whenever the fly enters this side. In a subsequent memory test without heat it keeps avoiding the heat-associated side. The memory mutants dunce1 and rutabaga1 successfully avoid the heated side but show no avoidance in the memory test. Wildtype flies can be trained to successively avoid alternating sides in a reversal conditioning experiment. Every single… Expand
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