A new orally active positive inotropic substance: AR-L 115 BS.

Abstract

In the course of diagnostic cardiac catheterisation in 6 patients suspected of having coronary heart disease 2-[(2-methoxy)-4-methylsulfinyl)phenyl]-1H-imidazol[4,5-b]pyridine (AR-L 115 BS) was administered to see whether an improvement in left ventricular function could be achieved. 30 min after oral administration of the drug there was an increase in the… (More)

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