A new nucleotide involved in the stringent response in Escherichia coli. Guanosine 5'-diphosphate-3'-monophosphate.


A novel nucleotide has been detected in Escherichia coli subjected to the stringent response. However, this nucleotide does not accumulate in relA+ cells subjected to heat shock, in which guanosine 5'-diphosphate-3'-diphosphate does accumulate but stable RNA synthesis is not restricted. The intracellular level of this new nucleotide thus correlates well… (More)


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