A new mutation, R563Q, of the beta subunit of the epithelial sodium channel associated with low-renin, low-aldosterone hypertension.

@article{Rayner2003ANM,
  title={A new mutation, R563Q, of the beta subunit of the epithelial sodium channel associated with low-renin, low-aldosterone hypertension.},
  author={Brian L. Rayner and Elizabeth Patricia Owen and Judy A. C. King and Steven G Soule and Heleen Vreede and Lionel Henry Opie and David L De Marais and James S. Davidson},
  journal={Journal of hypertension},
  year={2003},
  volume={21 5},
  pages={921-6}
}
OBJECTIVE To determine the relationship between R563Q, a mutation of the renal epithelial sodium channel, and hypertension. METHODS Hypertensive patients with low renin and aldosterone, hypokalemia or resistant hypertension were selected for DNA analysis. Genomic DNA encoding the C-terminal domain of the epithelial sodium channel beta subunit from… CONTINUE READING