A new monoclonal antibody, UFT-4, reacting with rat Kupffer cells. Immunohistochemical and immunoelectron microscopical analysis with reestimation of the reticuloendothelial system.

@article{Ukai1988ANM,
  title={A new monoclonal antibody, UFT-4, reacting with rat Kupffer cells. Immunohistochemical and immunoelectron microscopical analysis with reestimation of the reticuloendothelial system.},
  author={Koji Ukai and Keita Terashima and Yuriko Fujii and Yoichi Imai},
  journal={Acta pathologica japonica},
  year={1988},
  volume={38 11},
  pages={1391-403}
}
A new monoclonal antibody, designated UFT-4, reacting with rat Kupffer cells, was produced using sinusoidal liver-cell fraction as an immunogen. Immunohistochemically, UFT-4 reacted with Kupffer cells, interdigitating cells (IDCs), sinus endothelial cells of the spleen, a proportion of reticulum cells, smooth muscle fibers, choroid plexus epithelia and some macrophages. Immunoelectron microscopy disclosed two types of intracytoplasmic positivity: a striated type and a diffuse type. Both… CONTINUE READING