A new model for diffuse brain injury by rotational acceleration: II. Effects on extracellular glutamate, intracranial pressure, and neuronal apoptosis.

@article{Runnerstam2001ANM,
  title={A new model for diffuse brain injury by rotational acceleration: II. Effects on extracellular glutamate, intracranial pressure, and neuronal apoptosis.},
  author={Magnus Runnerstam and Feng Bao and Ying Huang and Jing-Shan Shi and Esperanza Guti{\'e}rrez and Anders Hamberger and Hans A. Hansson and David Viano and Kenneth H. Haglid},
  journal={Journal of neurotrauma},
  year={2001},
  volume={18 3},
  pages={
          259-73
        }
}
The aim of this study is to monitor excitatory amino acids (EAAs) in the extracellular fluids of the brain and to characterize regional neuronal damage in a new experimental model for brain injury, in which rabbits were exposed to 180-260 krad/s2 rotational head acceleration. This loading causes extensive subarachnoid hemorrhage, focal tissue bleeding, reactive astrocytosis, and axonal damage. Animals were monitored for intracranial pressure (ICP) and for amino acids in the extracellular fluids… CONTINUE READING
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