A new method to determine dose-effect relations for local lung-function changes using correlated SPECT and CT data.


PURPOSE To determine dose-effect relations for regional lung-function changes after radiotherapy. METHODS Single Photon Emission Computed Tomography (SPECT) was performed to quantify regional ventilation and perfusion. CT scans were used to calculate the three-dimensional (3-D) dose distribution. Both SPECT and CT scans were performed prior to… (More)