A new method for the analysis of cohort studies: implications of the multistage theory of carcinogenesis applied to occupational arsenic exposure.

C. C. Brown, K. C. Chu
Published 1983 in Environmental health perspectives

Abstract

Implications of the multistage theory of carcinogenesis for evaluating the effect of exposure to carcinogens in the workplace are described. This theory predicts different patterns of excess risk related to duration of exposure, age at initial exposure, and follow-up time since exposure stopped, depending upon which stage of the carcinogenic process is… (More)

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11 Figures and Tables

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References

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Testing hypotheses in case-control studies--equivalence of Mantel-Haenszel statistics and logit score tests.

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Occupational and environmental risks in and around a smelter in northern Sweden. II. Chromosomal aberrations in workers exposed to arsenic.

I Nordenson, G Beckman, L Beckman, S Nordström
Hereditas
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A new method for the analysis of cohort studies: implications of the multistage theory of carcinogenesis applied to occupational arsenic exposure.

Abstract

Topics

11 Figures and Tables

Cited By

Analysis of genomic dose-response information on arsenic to inform key events in a mode of action for carcinogenicity.

Health risk assessment for arsenic contaminated soil.

World Health Organization International Agency for Research on Cancer Statistical Methods in Cancer Research

Exposure and Health Effects

Neoplastic disease through the human life span

Trends in cigarette consumption cannot fully explain trends in British lung cancer rates.

Incidence of internal cancers and ingested inorganic arsenic: a seven-year follow-up study in Taiwan.

Human carcinogenesis by arsenic.

Bladder cancer mortality of workers exposed to aromatic amines: analysis of models of carcinogenesis.

References

Multistage models and primary prevention of cancer.

On the robustness of combined tests for trends in proportions

Principles of Genotic Toxicity

Some Metals and Metallic Compounds (Evaluation of the Carcinogenic Risk of Chemicals to Humans

Chromosome aberrations in psoriatic patients treated with arsenic

Testing hypotheses in case-control studies--equivalence of Mantel-Haenszel statistics and logit score tests.

Two-event models for carcinogenesis Incidence curves for childhood and adult tumors

Cigarette smoking and bronchial carcinoma: dose and time relationships among regular smokers and lifelong non-smokers.

Mortality experience of arsenic-exposed workers.

Occupational and environmental risks in and around a smelter in northern Sweden. II. Chromosomal aberrations in workers exposed to arsenic.

Slides referencing similar topics

A new method for the analysis of cohort studies: implications of the multistage theory of carcinogenesis applied to occupational arsenic exposure.

Abstract

Topics

11 Figures and Tables

Cited By

Analysis of genomic dose-response information on arsenic to inform key events in a mode of action for carcinogenicity.

Health risk assessment for arsenic contaminated soil.

World Health Organization International Agency for Research on Cancer Statistical Methods in Cancer Research

Exposure and Health Effects

Neoplastic disease through the human life span

Trends in cigarette consumption cannot fully explain trends in British lung cancer rates.

Incidence of internal cancers and ingested inorganic arsenic: a seven-year follow-up study in Taiwan.

Human carcinogenesis by arsenic.

Bladder cancer mortality of workers exposed to aromatic amines: analysis of models of carcinogenesis.

References

Multistage models and primary prevention of cancer.

On the robustness of combined tests for trends in proportions

Principles of Genotic Toxicity

Some Metals and Metallic Compounds (Evaluation of the Carcinogenic Risk of Chemicals to Humans

Chromosome aberrations in psoriatic patients treated with arsenic

Testing hypotheses in case-control studies--equivalence of Mantel-Haenszel statistics and logit score tests.

Two-event models for carcinogenesis Incidence curves for childhood and adult tumors

Cigarette smoking and bronchial carcinoma: dose and time relationships among regular smokers and lifelong non-smokers.

Mortality experience of arsenic-exposed workers.

Occupational and environmental risks in and around a smelter in northern Sweden. II. Chromosomal aberrations in workers exposed to arsenic.

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