A new method for detecting anaerobic threshold by gas exchange.

  title={A new method for detecting anaerobic threshold by gas exchange.},
  author={W. L. Beaver and K. Wasserman and B. Whipp},
  journal={Journal of applied physiology},
  volume={60 6},
Excess CO2 is generated when lactate is increased during exercise because its [H+] is buffered primarily by HCO-3 (22 ml for each meq of lactic acid). We developed a method to detect the anaerobic threshold (AT), using computerized regression analysis of the slopes of the CO2 uptake (VCO2) vs. O2 uptake (VO2) plot, which detects the beginning of the excess CO2 output generated from the buffering of [H+], termed the V-slope method. From incremental exercise tests on 10 subjects, the point of… Expand
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  • 204
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  • 482
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  • 1,863
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  • 167
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  • 435
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  • 196
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  • 253
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  • 380