A new membrane antigen revealed by monoclonal antibodies is associated with motoneuron axonal pathways.

@article{Tanaka1989ANM,
  title={A new membrane antigen revealed by monoclonal antibodies is associated with motoneuron axonal pathways.},
  author={Hideyuki Tanaka and Akemi Agata and Kunihiko Obata},
  journal={Developmental biology},
  year={1989},
  volume={132 2},
  pages={
          419-35
        }
}
Chick embryonic motoneurons selectively grow out from the spinal cord as the first step of their selective axonal growth. In order to detect the molecules responsible for motoneuron outgrowth from the cord, we produced and immunohistochemically screened many monoclonal antibodies (MAbs) against cord and somite. We found that two of them, called M7412 and M7902, selectively bound to the cell surface of the anterior half of the sclerotome, where motoneurons selectively extend their axons… CONTINUE READING
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