A new marker of maturation in the cervix: the estrogen-regulated 24K protein.

@article{Dressler1986ANM,
  title={A new marker of maturation in the cervix: the estrogen-regulated 24K protein.},
  author={Lynn G. Dressler and I Ramzy and George W. Sledge and William L. McGuire},
  journal={Obstetrics and gynecology},
  year={1986},
  volume={68 6},
  pages={825-31}
}
The presence of an estrogen-regulated protein (24K) in normal, dysplastic, metaplastic, and neoplastic cervical epithelium correlates with histologic criteria for squamous cell maturation. The 24K protein, originally discovered in the MCF-7 breast cancer cell line, was studied in 51 cases by the modified immunoperoxidase Avidin-Biotin Complex method, using an anti-24K mouse monoclonal antibody. Immunostained sections were compared to hematoxylin-and-eosin-stained sections cut from the same… CONTINUE READING