A new intracellular pathway of haem detoxification in the midgut of the cattle tick Boophilus microplus: aggregation inside a specialized organelle, the hemosome.

@article{Lara2003ANI,
  title={A new intracellular pathway of haem detoxification in the midgut of the cattle tick Boophilus microplus: aggregation inside a specialized organelle, the hemosome.},
  author={Fl{\'a}vio Alves Lara and Ulysses Lins and Gabriela O Paiva-Silva and Igor C. Almeida and Cl{\'a}udia M. S. Braga and Fl{\'a}vio Costa Miguens and Pedro Lagerblad de Oliveira and Mar{\'i}lvia Dansa-Petretski},
  journal={The Journal of experimental biology},
  year={2003},
  volume={206 Pt 10},
  pages={1707-15}
}
The hard tick Boophilus microplus ingests large volumes of cattle blood, as much as 100 times its own mass before feeding. Huge amounts of haem are produced during haemoglobin digestion, which takes place inside acidic lysosomal-type vacuoles of the digest cells of the midgut. Haem is a promoter of free radical formation, so haemoglobin digestion poses an intense oxidative challenge to this animal. In the present study we followed the fate of the haem derived from haemoglobin hydrolysis in the… CONTINUE READING

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