A new in vitro mouse oligodendrocyte precursor cell migration assay reveals a role for integrin-linked kinase in cell motility

@inproceedings{OMeara2016ANI,
  title={A new in vitro mouse oligodendrocyte precursor cell migration assay reveals a role for integrin-linked kinase in cell motility},
  author={Ryan W. O’Meara and Sarah E. Cummings and John-Paul Michalski and Rashmi Kothary},
  booktitle={BMC Neuroscience},
  year={2016}
}
The decline of remyelination in chronic multiple sclerosis (MS) is in part attributed to inadequate oligodendrocyte precursor cell (OPC) migration, a process governed by the extracellular matrix (ECM). Elucidating the mechanisms underlying OPC migration is therefore an important step towards developing new therapeutic strategies to promote myelin repair… CONTINUE READING