A new improved Stability-Indicating RP-HPLC method for Determination of Diosmin and hesperidin in combination

  • Anwer M.K
  • Published 2014


A rapid, simple, precise and cost effective stability-indicating RP-HPLC method has been developed and validated for determination of diosmin and hesperidin in combination. The mobile phase consisted of mixture of methanol: water (45:55 v/v). UV detection was performed at 346 nm. The method was linear over the concentration ranges 4.8-7.2 μg mL, and 2040 μg… (More)