A new human pleomorphic hepatocellular carcinoma cell line, KYN-2.

  title={A new human pleomorphic hepatocellular carcinoma cell line, KYN-2.},
  author={Hirohisa Yano and Masafumi Maruiwa and Takayoshi Murakami and Kenji Fukuda and Yasuhiro Ito and Shuji Sugihara and Masamichi Kojiro},
  journal={Acta pathologica japonica},
  volume={38 8},
A new human hepatocellular carcinoma (HCC) cell line, KYN-2, has been established from a surgical specimen obtained from a 52-year-old Japanese male HCC patient. The originally resected HCC was classified as pleomorphic HCC corresponding to Edmondson-Steiner's grade III with a thick trabecular to solid arrangement. The cell line has been maintained for 17 months through 35 passages. Morphologically, the KYN-2 cells have retained the characteristics of the original HCC, being pleomorphic and… CONTINUE READING
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