A new horizon into the pathobiology, etiology and treatment of migraine.

@article{Dhillon2011ANH,
  title={A new horizon into the pathobiology, etiology and treatment of migraine.},
  author={K. S. Dhillon and Jasmer Singh and J. S. Lyall},
  journal={Medical hypotheses},
  year={2011},
  volume={77 1},
  pages={
          147-51
        }
}
Sexual dimorphism in the prevalence of migraine (70% women 30% men) suggests the involvement of reproductive hormones in a women's life. Excessive estrogen during menstruation directly stimulate estrogen receptor alpha thickly populated in trigeminal ganglia and periaqueductal gray which manifest as menstrual migraine. In contrast increased progesterone during pregnancy evokes progesterone receptors A/B, which coexist with ERs, providing complete remission from migraine episodes. Moreover… Expand
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References

SHOWING 1-10 OF 29 REFERENCES
Potential role of female sex hormones in the pathophysiology of migraine.
Effects of Oestrogen on Trigeminal Ganglia in Culture: Implications for Hormonal Effects on Migraine
Migraine and the Hypothalamus
  • K. Alstadhaug
  • Medicine
  • Cephalalgia : an international journal of headache
  • 2009
Role of melatonin in neurodegenerative diseases
New drugs in migraine treatment and prophylaxis: telcagepant and topiramate
Neurobiology of migraine
Reducing oxidative/nitrosative stress: a newly-discovered genre for melatonin
...
1
2
3
...