A new histobiochemical method to analyze sialylation on cell-surface glycoproteins of head and neck squamous-cell carcinomas

@article{Bergler1997ANH,
  title={A new histobiochemical method to analyze sialylation on cell-surface glycoproteins of head and neck squamous-cell carcinomas},
  author={Wolfgang F. Bergler and Frank Riedel and Reinhard Schwartz-Albiez and H. J. Gross and Karl Hoermann},
  journal={European Archives of Oto-Rhino-Laryngology},
  year={1997},
  volume={254},
  pages={437-441}
}
Oncogenic transformation is often accompanied by alterations of glycosylation on a tumor cell's surface, which may contribute to uncontrolled cell growth. The sialoglycans and degree of sialylation on the cell surface are of increasing interest because of their possible role in metastasis and tissue invasion. Since primary tumors and metastases may differ in the degree of sialylation, we examined the expression of sialic acid as a terminal constituent of lactosaminyl glycans on the cell… CONTINUE READING