A new high-performance heterologous fungal expression system based on regulatory elements from the Aspergillus terreus terrein gene cluster

@inproceedings{Gressler2015ANH,
  title={A new high-performance heterologous fungal expression system based on regulatory elements from the Aspergillus terreus terrein gene cluster},
  author={Markus Gressler and Peter Hortschansky and Elena Geib and Matthias Brock},
  booktitle={Front. Microbiol.},
  year={2015}
}
Recently, the Aspergillus terreus terrein gene cluster was identified and selected for development of a new heterologous expression system. The cluster encodes the specific transcription factor TerR that is indispensable for terrein cluster induction. To identify TerR binding sites, different recombinant versions of the TerR DNA-binding domain were analyzed for specific motif recognition. The high affinity consensus motif TCGGHHWYHCGGH was identified from genes required for terrein production… CONTINUE READING
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