A new heredo-familial neurological syndrome.

Abstract

This report describes a family in which a heredofamilial neurological disorder of unusual type appears to have been transmitted from an affected father to at least five of his children. The main features of the condition consisted of athetosis, hypotonia, absent tendon reflexes, extensor plantar responses, mental retardation and periodic febrile attacks occurring simultaneously in several members of the family with episodes of prolonged unconsciousness. Ford (1952) gave an account of the various hereditary and familial encephalomyelitic and demyelinating diseases, but none of the clinical syndromes he described correspond with our cases, nor have we been able in a search of the literature to find records of cases similar to our own. We therefore present the following case reports in the belief that they represent a hitherto undescribed disease.

Cite this paper

@article{Harvey1955ANH, title={A new heredo-familial neurological syndrome.}, author={Christopher C. Harvey and James Haworth and John Lorber}, journal={Archives of disease in childhood}, year={1955}, volume={30 152}, pages={338-44} }