A new heat shock protein that binds nucleic acids.

@article{Korber1999ANH,
  title={A new heat shock protein that binds nucleic acids.},
  author={Philipp Korber and Thomas Zander and Daniel Herschlag and James C. A. Bardwell},
  journal={The Journal of biological chemistry},
  year={1999},
  volume={274 1},
  pages={
          249-56
        }
}
We describe the isolation of Hsp15, a new, very abundant heat shock protein that binds to DNA and RNA. Hsp15 is well conserved and related to a number of RNA-binding proteins, including ribosomal protein S4, RNA pseudouridine synthase, and tyrosyl-tRNA synthetase. The region shared between these proteins appears to represent a common, but previously unrecognized, RNA binding motif. Filter binding studies showed that Hsp15 binds to a 17-mer single-stranded RNA with a dissociation constant of 9… CONTINUE READING

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