A new frontier for an old drug? A word of caution for beta-blockers in sepsis!

Abstract

Recent promising findings indicate a possible benefit of β-blockade in septic patients. Ongoing trials on esmolol in septic shock are investigating its hemodynamic effects, focusing on heart rate control and echocardiographic changes, as well as potential anti-inflammatory effects. However, given the complex physiology of sepsis and pharmacological effects on β-blockade, large multi-center trials are essential before such a therapy may be applied safely.

DOI: 10.1185/03007995.2015.1085371

Cite this paper

@article{Maybauer2015ANF, title={A new frontier for an old drug? A word of caution for beta-blockers in sepsis!}, author={Marc Oliver Maybauer and Dirk M. Maybauer}, journal={Current medical research and opinion}, year={2015}, volume={31 10}, pages={1829-30} }