A new formulation of selegiline: improved bioavailability and selectivity for MAO-B inhibition

@article{Clarke2003ANF,
  title={A new formulation of selegiline: improved bioavailability and selectivity for MAO-B inhibition},
  author={Anthony Clarke and Francesca Mary Brewer and E. Stewart Johnson and N. Mallard and Florian Hartig and S. Taylor and T. H. Corn},
  journal={Journal of Neural Transmission},
  year={2003},
  volume={110},
  pages={1241-1255}
}
Summary. Seven randomised comparative studies were conducted in healthy volunteers to compare the pharmacokinetic and pharmacodynamic profiles of selegiline hydrochloride in a new formulation designed for buccal absorption “Zydis Selegiline” (1.25–10 mg) with conventional selegiline hydrochloride tablets “conventional selegiline tablets” (10 mg). A total of 156 healthy volunteers participated in these studies. Plasma concentrations of selegiline and its primary metabolites, N… 
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Summary. Three studies were performed using a fast dissolving formulation of selegiline hydrochloride designed for buccal absorption “Zydis Selegiline”. The aim of the first study was to compare the
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