A new formulation for orally disintegrating tablets using a suspension spray-coating method.

Abstract

The aim of this study was to design a new orally disintegrating tablet (ODT) that has high tablet hardness and a fast oral disintegration rate using a new preparation method. To obtain rapid disintegration granules (RDGs), a saccharide, such as trehalose, mannitol, or lactose, was spray-coated with a suspension of corn starch using a fluidized-bed… (More)
DOI: 10.1016/j.ijpharm.2009.08.010

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