A new family of phosphoinositide phosphatases in microorganisms: identification and biochemical analysis

Abstract

Phosphoinositide metabolism is essential to membrane dynamics and impinges on many cellular processes, including phagocytosis. Modulation of phosphoinositide metabolism is important for pathogenicity and virulence of many human pathogens, allowing them to survive and replicate in the host cells. Phosphoinositide phosphatases from bacterial pathogens are… (More)
DOI: 10.1186/1471-2164-11-457

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